THE GEM-HANDLE AS CONVENIENT LABELING STRATEGY FOR BIMODAL SINGLE-DOMAIN ANTIBODY-BASED TRACERS CARRYING 99MTC AND A NEAR-INFRARED FLUORESCENT DYE FOR INTRA-OPERATIVE DECISION-MAKING

Intra-operative fluorescence imaging has demonstrated its ability to improve tumor lesion identification.However, the limited tissue penetration of the fluorescent signals hinders the detection of deep-lying or occult lesions.Integrating fluorescence imaging with SPECT and/or intra-operative gamma-probing synergistically combines the deep tissue pe

Concurrent use of stimulants (e.g., methamphetamine) and opioids (e.g., fentanyl) has become increasingly common in recent years and continues to pose an enormous health burden, worldwide.Despite the prevalence, relatively little is known about interactions between the reinforcing effects of stimulants and opioids in this pattern of polysubstance u

Production planning is an activity to obtain products in accordance with the needs of two parties, namely companies and consumers.Production planning is important in the industry in order to achieve optimal profits.In the rattan handicraft business, furniture faces problems in production planning.The production process is carried out based on the a

Abstract Inference and analysis of gene regulatory networks (GRNs) require software that integrates multi-omic data from various sources.The Network Zoo (netZoo; netzoo.github.io) is a collection of open-source methods to infer GRNs, conduct differential network analyses, estimate community structure, and explore the transitions between biological

A train operation optimization by minimizing its traction energy subject to various constraints is carried out using nature-inspired evolutionary algorithms.The optimization Filters process results in switching points that initiate cruising and coasting phases of the driving.Due to nonlinear optimization formulation of the problem, nature-inspired